Stem Cells & Perinatal Therapies
Cell and perinatal products: promise, evidence, quality and clinical limitations.
Sjögren’s disease
Understand the diagnosis. Navigate care. Examine what is changing.
By Olga Goodman, MD · A RheumaView publication
Patient quizzes are free. Open demos need no registration; the other quizzes require a free account.
Matching chapters, quizzes and resources
Sjögren’s patient quizzes
Short stories, a little humour and explanations you can explore at your own pace.
Explore the chapters
Start with the question that matters to you. Open a topic to see its full chapters.
Diagnosis & uncertainty
Make sense of symptoms, tests and an uncertain diagnosis.Show chapters+
Dryness & gland care
Protect the eyes and mouth and understand gland function.Show chapters+
Systemic manifestations
Explore disease beyond dryness and differences between phenotypes.Show chapters+
Treatment & response
Connect treatment choices with goals and meaningful outcomes.Show chapters+
Daily life & follow-up
Address fatigue, function, monitoring and different life stages.Show chapters+
Research & new approaches
Examine clinical trials, emerging treatments and biological questions.Show chapters+
Watch & explore
Visual explanations by Olga Goodman, MD. Film and animation captions are in English.
From dryness to disease modification
A visual introduction to systemic disease and treatment research. Published June 2026; use the current chapters for evidence and regulatory updates.
Explore new treatments ↗Disease, treatment and the BAFF pathway
Watch the mechanism close-up, then explore the full 31-step sequence at your own pace.
Open the interactive journey ↗Related reading
Afraid of the medication. What about the disease?
Medication fears, benefits, side effects, and the cost of waiting. Read the evidence and prepare your questions.
Patient education supports conversations with your care team and does not replace individual diagnosis or treatment.
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The Evidence Behind the Prescription
CSQ-SJD-TREAT. Advanced professional Sjögren’s disease (Sjogren syndrome) quiz and interactive module: JOQUER, RepurpSS-II, TRACTISS, nintedanib for progressive ILD, neuropathic pain, tubulointerstitial nephritis (TIN), and strong recommendations with very low certainty. English. Open demo; no registration required.
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Beyond Dryness
CPQ-SJD-SYSTEMIC. Sjögren disease (SjS, Sjogren syndrome). Patient quiz and interactive module. Seven questions. Open demo; no registration. EN/RU/ES/PL. Sjögren’s disease can affect organs far from the eyes and mouth, and the amount of dryness does not predict it. Seven questions check whether you can recognise the symptoms that deserve a specific test, and the ones that should not wait. Не только сухость · Más allá de la sequedad · Nie tylko suchość RVQP1:eyJjYXNlSWQiOiJDUFEtU0pELVNZU1RFTUlDIiwiYXVkaWVuY2UiOiJwYXRpZW50cyIsImFjY2VzcyI6ImRlbW8iLCJsYW5ndWFnZXMiOlsiZW4iLCJydSIsImVzIiwicGwiXSwidG9waWMiOiJzam9ncmVuIiwiZm9ybWF0IjpbImNhc2UiLCJtb2R1bGUiXSwib3JkZXIiOjMsImxvY2FsZXMiOnsiZW4iOnsidGl0bGUiOiJCZXlvbmQgRHJ5bmVzcyIsImRlc2NyaXB0aW9uIjoiU2rDtmdyZW4ncyBkaXNlYXNlIGNhbiBhZmZlY3Qgb3JnYW5zIGZhciBmcm9tIHRoZSBleWVzIGFuZCBtb3V0aCwgYW5kIHRoZSBhbW91bnQgb2YgZHJ5bmVzcyBkb2VzIG5vdCBwcmVkaWN0IGl0LiBTZXZlbiBxdWVzdGlvbnMgY2hlY2sgd2hldGhlciB5b3UgY2FuIHJlY29nbmlzZSB0aGUgc3ltcHRvbXMgdGhhdCBkZXNlcnZlIGEgc3BlY2lmaWMgdGVzdCwgYW5kIHRoZSBvbmVzIHRoYXQgc2hvdWxkIG5vdCB3YWl0LiIsImtleXdvcmRzIjoiQ291Z2ggYW5kIGJyZWF0aGxlc3NuZXNzIHdpdGggYSBub3JtYWwgY2hlc3QgWC1yYXkgQnVybmluZyBmZWV0LCB3ZWFrbmVzcyBhbmQgd2hhdCBuZXJ2ZSB0ZXN0cyBjYW4gbWlzcyBMb3cgcG90YXNzaXVtIGFuZCB0aGUga2lkbmV5cyBMeW1waG9tYTogcmVhbCByaXNrLCBrZXB0IGluIHByb3BvcnRpb24ifSwicnUiOnsidGl0bGUiOiLQndC1INGC0L7Qu9GM0LrQviDRgdGD0YXQvtGB0YLRjCIsImRlc2NyaXB0aW9uIjoi0JHQvtC70LXQt9C90Ywg0KjRkdCz0YDQtdC90LAg0LzQvtC20LXRgiDQt9Cw0YLRgNCw0LPQuNCy0LDRgtGMINC+0YDQs9Cw0L3RiyDQtNCw0LvQtdC60L4g0L7RgiDQs9C70LDQtyDQuCDRgNGC0LAsINC4INCy0YvRgNCw0LbQtdC90L3QvtGB0YLRjCDRgdGD0YXQvtGB0YLQuCDRjdGC0L7Qs9C+INC90LUg0L/RgNC10LTRgdC60LDQt9GL0LLQsNC10YIuINCh0LXQvNGMINCy0L7Qv9GA0L7RgdC+0LIg0L/RgNC+0LLQtdGA0Y/Rgiwg0YPQvNC10LXRgtC1INC70Lgg0LLRiyDRgNCw0YHQv9C+0LfQvdCw0LLQsNGC0Ywg0YHQuNC80L/RgtC+0LzRiywg0LrQvtGC0L7RgNGL0LUg0YLRgNC10LHRg9GO0YIg0LrQvtC90LrRgNC10YLQvdC+0LPQviDQvtCx0YHQu9C10LTQvtCy0LDQvdC40Y8sINC4INGC0LUsINGBINC60L7RgtC+0YDRi9C80Lgg0L3QtdC70YzQt9GPINC20LTQsNGC0YwuIiwia2V5d29yZHMiOiLQmtCw0YjQtdC70Ywg0Lgg0L7QtNGL0YjQutCwINC/0YDQuCDQvdC+0YDQvNCw0LvRjNC90L7QvCDRgNC10L3RgtCz0LXQvdC1INCz0YDRg9C00L3QvtC5INC60LvQtdGC0LrQuCDQltC20LXQvdC40LUg0LIg0YHRgtC+0L/QsNGFLCDRgdC70LDQsdC+0YHRgtGMINC4INGC0L4sINGH0YLQviDQvNC+0LPRg9GCINC/0YDQvtC/0YPRgdGC0LjRgtGMINC40YHRgdC70LXQtNC+0LLQsNC90LjRjyDQvdC10YDQstC+0LIg0J3QuNC30LrQuNC5INC60LDQu9C40Lkg0Lgg0L/QvtGH0LrQuCDQm9C40LzRhNC+0LzQsDog0YDQtdCw0LvRjNC90YvQuSDRgNC40YHQuiDQsiDQv9GA0LDQstC40LvRjNC90L7QvCDQvNCw0YHRiNGC0LDQsdC1In0sImVzIjp7InRpdGxlIjoiTcOhcyBhbGzDoSBkZSBsYSBzZXF1ZWRhZCIsImRlc2NyaXB0aW9uIjoiTGEgZW5mZXJtZWRhZCBkZSBTasO2Z3JlbiBwdWVkZSBhZmVjdGFyIGEgw7NyZ2Fub3MgYWxlamFkb3MgZGUgbG9zIG9qb3MgeSBsYSBib2NhLCB5IGxhIGludGVuc2lkYWQgZGUgbGEgc2VxdWVkYWQgbm8gbG8gcHJlZGljZS4gU2lldGUgcHJlZ3VudGFzIGNvbXBydWViYW4gc2kgcmVjb25vY2UgbG9zIHPDrW50b21hcyBxdWUgbWVyZWNlbiB1bmEgcHJ1ZWJhIGNvbmNyZXRhIHkgbG9zIHF1ZSBubyBkZWJlbiBlc3BlcmFyLiIsImtleXdvcmRzIjoiVG9zIHkgZmFsdGEgZGUgYWlyZSBjb24gdW5hIHJhZGlvZ3JhZsOtYSBkZSB0w7NyYXggbm9ybWFsIEFyZG9yIGVuIGxvcyBwaWVzLCBkZWJpbGlkYWQgeSBsbyBxdWUgbGFzIHBydWViYXMgZGUgbmVydmlvcyBwdWVkZW4gcGFzYXIgcG9yIGFsdG8gRWwgcG90YXNpbyBiYWpvIHkgbG9zIHJpw7FvbmVzIExpbmZvbWE6IHVuIHJpZXNnbyByZWFsLCBlbiBzdSBqdXN0YSBtZWRpZGEifSwicGwiOnsidGl0bGUiOiJOaWUgdHlsa28gc3VjaG/Fm8SHIiwiZGVzY3JpcHRpb24iOiJDaG9yb2JhIFNqw7ZncmVuYSBtb8W8ZSBvYmVqbW93YcSHIG5hcnrEhWR5IG9kbGVnxYJlIG9kIG9jenUgaSB1c3QsIGEgbmFzaWxlbmllIHN1Y2hvxZtjaSB0ZWdvIG5pZSBwcnpld2lkdWplLiBTaWVkZW0gcHl0YcWEIHNwcmF3ZHppLCBjenkgcm96cG96bmFqZXN6IG9iamF3eSwga3TDs3JlIHd5bWFnYWrEhSBrb25rcmV0bmVnbyBiYWRhbmlhLCBvcmF6IHRlLCB6IGt0w7NyeW1pIG5pZSB3b2xubyBjemVrYcSHLiIsImtleXdvcmRzIjoiS2FzemVsIGkgZHVzem5vxZvEhyBwcnp5IHByYXdpZMWCb3d5bSB6ZGrEmWNpdSBrbGF0a2kgcGllcnNpb3dlaiBQaWVjemVuaWUgc3TDs3AsIG9zxYJhYmllbmllIGkgdG8sIGNvIGJhZGFuaWEgbmVyd8OzdyBtb2fEhSBwcnplb2N6ecSHIE5pc2tpIHBvdGFzIGEgbmVya2kgQ2jFgm9uaWFrOiByZWFsbmUgcnl6eWtvIHdlIHfFgmHFm2Npd3ljaCBwcm9wb3JjamFjaCJ9fX0=
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The Reassuring Scan
RV-SJPRO-03. Ninety-two percent of what, exactly? Professional Sjögren’s disease (Sjogren syndrome) quiz. Anti-SSA-negative disease and discordant tests. Open demo; EN / RU / ES / PL; no registration required.
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Tears & Saliva — RheumaPlay
Drops, gels, plugs, pills and a dentist who means it. Seven rounds on eye, mouth and tooth care — and on not becoming a product collector.
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A Week with Sjögren’s: Greta
Greta is 41, a video editor, and this week a documentary about lighthouses is due on Friday. She was diagnosed with Sjögren’s two years ago; her eyes are the loudest part of it, her mouth a close second. She works at two large screens with a desk fan, a bottle of eye drops and Pixel, a small grey dog who believes every deadline is a walk postponed.
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Follow the Organ, Not the Antibody
CSQ-SJD-MONITOR. Advanced professional Sjögren’s disease (Sjogren syndrome) quiz and interactive module: screening ultrasound, lymphoma warning features, AAO 2025 hydroxychloroquine (HCQ) retinal screening, PFT intervals, cryoglobulinaemic neuropathy, ACA and pulmonary arterial hypertension (PAH) surveillance. English. Open demo; no registration required.
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Dermatology–Rheumatology IV · Purpura, vasculitis and lupus — Clinical Rounds
Work through purpura, biopsy decisions, cryoglobulinemia, urticarial vasculitis, occlusive vasculopathy and difficult cutaneous lupus decisions.
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What Each Treatment Is For
CPQ-SJD-TREAT. Sjögren disease (SjS, Sjogren syndrome). Patient quiz and interactive module. Seven questions. Open demo; no registration. EN/RU/ES/PL. No single medicine ‘treats the Sjögren’s.’ Each one is chosen for a particular problem and judged against that problem. Seven questions check what the main treatments can realistically do, and how to tell whether yours is doing its job. Для чего нужно каждое лечение · Para qué sirve cada tratamiento · Do czego służy każde leczenie RVQP1: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Burning Feet and a Bottle of B6
RV-SJPRO-04. “Normal EMG” is not a synonym for “normal nerves”. Professional Sjögren’s disease (Sjogren syndrome) quiz. Systemic Sjögren’s disease: an organ atlas for clinical decisions. Open demo; EN / RU / ES / PL; no registration required.
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Beyond the Glands — RheumaPlay
Lungs, nerves, kidneys, skin, blood. Seven rounds on how organs get assessed in Sjögren’s — and why ‘systemic’ does not mean ‘everything, always’.
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A Week with Sjögren’s: Bruno
Bruno is 62, a retired postman with a Sjögren’s diagnosis that is four years old and, until now, mostly about a dry mouth and a drawer of lozenges. He walks six kilometres a day out of habit, reads a patient forum out of curiosity, and lives with his wife Ilse and Admiral, an African grey parrot who repeats whatever was said most recently and most loudly, which this week will be a problem.
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Glands, Pregnancy and a Sense of Proportion
CSQ-SJD-GLAND-REPRO. Advanced professional Sjögren’s disease (Sjogren syndrome) quiz and interactive module: preservative-free tears, pilocarpine, cevimeline, systemic therapy for dryness, acoltremon (COMET), anti-Ro/SSA pregnancy counselling, congenital heart block (CHB), PATCH and STOP BLOQ. English. Open demo; no registration required.
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Daily Life, Follow-up and Pregnancy
CPQ-SJD-LIFE. Sjögren disease (SjS, Sjogren syndrome). Patient quiz and interactive module. Seven questions. Open demo; no registration. EN/RU/ES/PL. Living well with Sjögren’s disease involves decisions that no single clinic visit covers. Seven questions check what the evidence says about fatigue, exercise, diet and pregnancy, and which changes should not wait for the next appointment. Повседневная жизнь, наблюдение и беременность · Vida diaria, seguimiento y embarazo · Codzienne życie, kontrole i ciąża RVQP1: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The Creatinine Alibi
RV-SJPRO-05. Filtration was never asked the right question. Professional Sjögren’s disease (Sjogren syndrome) quiz. Systemic Sjögren’s disease: an organ atlas for clinical decisions. Open demo; EN / RU / ES / PL; no registration required.
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Treatment Follows the Problem — RheumaPlay
There is no ‘mild to strong’ ladder — there is a target, a medicine for it and a date to check. Seven rounds on goals, hydroxychloroquine, organ-directed drugs and why guidelines disagree.
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Fatigue, Pain & Fog — RheumaPlay
‘Tired’ is not a diagnosis, and ‘your tests are fine’ is not a plan. Seven rounds on fatigue, pain that will not read the lab results, brain fog and what the exercise trials really showed.
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A Week with Sjögren’s: Lucía
Lucía is 36, a flight attendant on long-haul routes, and this week she flies a six-day rotation through three time zones. Her Sjögren’s was diagnosed last year; it lives mostly in her eyes and mouth, with a fatigue that arrives a day after it was invited. She packs light, except for the eye drops. At home, her cat Ñu — pronounced ‘nyoo’, named for a wildebeest and built like one — supervises the suitcase and attempts to board it.
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Purpura, Foot Drop and a Cold Tube
RV-SJPRO-06. The specimen went for a walk in January. Professional Sjögren’s disease (Sjogren syndrome) quiz. Systemic Sjögren’s disease: an organ atlas for clinical decisions. Open demo; EN / RU / ES / PL; no registration required.
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Food & Myths — RheumaPlay
No diet cures Sjögren’s, and no diet is forbidden by it. Seven rounds on what food can realistically change, which supplements earn their shelf space, and which ‘resets’ reset only your bank balance.
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Stable but Not Well: Irene
Irene is 50, a librarian, and knows where everything is — except her own energy. Her Sjögren’s was diagnosed three years ago; her joints are quiet, her blood tests are polite, and her rheumatologist uses the word “stable”. Irene is exhausted, achy and foggy by two in the afternoon. Her beagle Dewey sleeps sixteen hours a day and has never once been called stable.
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The Cough That Wasn’t ILD
RV-SJPRO-07. Spirometry alone is a sentence with the verb missing. Professional Sjögren’s disease (Sjogren syndrome) quiz. Systemic Sjögren’s disease: an organ atlas for clinical decisions. Open demo; EN / RU / ES / PL; no registration required.
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“Treat the Sjögren’s”
RV-SJPRO-08. Three words that cannot be assessed. Professional Sjögren’s disease (Sjogren syndrome) quiz. Treatment in Sjögren’s: define the target, then judge the response. Open demo; EN / RU / ES / PL; no registration required.
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Pregnancy & Life Stages — RheumaPlay
Anti-Ro, a baby’s heartbeat, a breastfeeding plan, a teenager with swollen glands, a man told it is ‘a women’s disease’. Seven rounds on Sjögren’s across a lifetime.
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Stable but Not Well: Olev
Olev is 64, a retired teacher, and has had Sjögren’s for twenty years. His disease is quiet: no joint swelling, no organ trouble, blood tests his rheumatologist calls boring. But twenty years of dry mouth have cost him eleven teeth, his salivary glands have little left, and his eyes sting no matter how many drops he puts in. His old dog Kalev is fourteen, drools generously, and has never understood why Olev is jealous.
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Dry Eyes, Wet Promises
RV-SJPRO-09. A Schirmer strip is not a regeneration certificate. Professional Sjögren’s disease (Sjogren syndrome) quiz. Glandular care in Sjögren’s: eyes, mouth, salivary function and prevention. Open demo; EN / RU / ES / PL; no registration required.
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Follow-up Without Panic — RheumaPlay
Feeling reasonably well is not a reason to vanish — and ‘stable’ is not a synonym for ‘cured’. Seven rounds on what gets checked, how often, and which lumps deserve a look.
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Stable but Not Well: Sanne
Sanne is 38, an architect, mother of four-year-old twins, and — according to everyone — looks great. Her Sjögren’s was diagnosed two years ago; her blood tests are quiet and her rheumatologist is pleased. Sanne is running on fumes, cannot hold a floor plan in her head past three o’clock, and is quietly furious that nobody can see it. Her partner Theo tries. Her cat Bisou does not try, and is the only one in the house who is never asked how she is.
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Two Percent and a Doppler
RV-SJPRO-10. A number is only as good as the pregnancy it was measured in. Professional Sjögren’s disease (Sjogren syndrome) quiz. Nutrition and special populations in Sjögren’s. Open demo; EN / RU / ES / PL; no registration required.
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The Pipeline & the Miracles — RheumaPlay
Breakthrough designation, phase III, ‘approved in one country’, stem cells and gland regrowth. Seven rounds on reading a treatment headline without buying a ticket you cannot use.
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Sjögren’s Disease: Beauty Care That Respects Dry Eyes and a Dry Mouth
Aesthetic care can still be discussed. The most useful plan considers comfort as well as appearance.
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Pulmonology–Rheumatology · Clinical Rounds
ILD: diagnosis and first-line choices; Progression, monitoring and antifibrotics; Airways, pleura and respiratory muscles; Acute respiratory emergencies; Drug toxicity and infection.
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Nephrology–Rheumatology · Clinical Rounds
Lupus nephritis: detection and tissue; Lupus nephritis: treatment over time; ANCA and anti-GBM glomerulonephritis; Tubulointerstitial disease and mimics; Kidney safety, CKD and transplantation.
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Neurology–Rheumatology · Clinical Rounds
Brain vessels and their mimics; Neuropsychiatric lupus and attribution; Peripheral nerve and ganglion; Systemic disease in the nervous system; Treatment, infection and the nervous system.
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Ophthalmology–Rheumatology · Clinical Rounds
Anterior uveitis, SpA and the gut; JIA-associated uveitis; Sclera, cornea and orbit; Drugs and the retina; Systemic uveitis and masquerades.
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Hematology–Rheumatology · Clinical Rounds
Macrophage activation and secondary HLH; Neutropenia, Felty and large granular lymphocytes; Cytopenias and haemolysis in lupus; Clones, gammopathy and Castleman; Drug-related cytopenia and coagulopathy.
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Oncology–Rheumatology · Clinical Rounds
Arthritis and polymyalgia on checkpoint inhibitors; Muscle, heart and glands on checkpoint inhibitors; Paraneoplastic and malignancy-related mimics; CAR-T and cell therapy in autoimmune disease; Cancer treatment meets rheumatology.
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Burning Feet at Fifty-Nine, Expert Level: Three Years of Decisions
Eight expert-level encounters in systemic Sjögren’s disease: neuropathy, cryoglobulinemic vasculitis, renal disease, lymphoma, pulmonary amyloid and antibody deficiency.
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A Violinist’s Cold Fingers, Expert Level: Three Years of Decisions
Eight expert-level encounters in ACA-positive Sjögren’s disease: diagnostic uncertainty, Raynaud’s, primary biliary cholangitis, systemic sclerosis overlap, renal crisis and pregnancy.
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Past the Headline
Twenty months with Sjögren’s disease for a patient who reads trial registries before breakfast and learns which numbers answer his own questions.
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The Invisible Half
Twenty-two months with Sjögren’s nerves, sleep and brain fog, for a crossword compiler whose problems rarely show on a routine blood test.